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Early life:
Mitra was born in Paddington, London, England, the daughter of Antony Mitra, who is a cosmetic surgeon, and Nora Downey. She has an older brother, Jason Wath Mitra, who is two years her senior, and a younger brother. Her father is of Indian and English descent, and her mother is Irish. In 1984, when Mitra was eight, her parents divorced, and she was sent to boarding school. She spent several years at two different schools, including Roedean, but Mitra claims she was eventually expelled from both of them.
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Mitra showed herself to the wider audiences playing the romantic interest of Christopher Lambert in Beowulf. Her first main role came as Scott Wolf's illicit love interest on Party of Five. In 2000, Mitra had a small role in the film Hollow Man, as a neighbor assaulted by Kevin Bacon's character. She had a main role in medical drama Gideon's Crossing, as Dr. Alejandra 'Ollie' Klein. Mitra then had roles in Ali G Indahouse; Sweet Home Alabama; Stuck on You, and leading roles in Highwaymen and Spartacus. Mitra appeared in the final season of The Practice as Tara Wilson, and continued that role into its spin-off Boston Legal, but left not long into the second season. In 2005, Mitra played the role of Kit McGraw during Season 3 of Nip/Tuck. Mitra then went on to appear in Skinwalkers, The Number 23 and Shooter. In 2008, Mitra starred in the lead role of the science fiction/action film Doomsday as Major Eden Sinclair, and in 2009 went on to star in Underworld: Rise of the Lycans as Sonja, the daughter of the powerful vampire elder Viktor (played by Bill Nighy)and is currently appearing in Stargate Universe.
Mitra appeared as the live action model for Lara Croft, the lead character in Eidos Interactive's Tomb Raider video game series. Mitra was ranked #46 on the Maxim Hot 100 Women of 2001. She stars in the 2010 Anders Anderson thriller film Stolen, on the side from Josh Lucas and Jon Hamm.
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Ghostbusters of East Finchley (1995) as Cass (as "Rona Mitra")
The Bill (1996) as Sarah Wickes
Lust for Glorious (1997) as French girl #1
The Man Who Made Husbands Jealous (1997) as Flora Seymour
The Pepsi Chart (1998) as herself (co-presenter)
A Kid in Aladdin's Palace (1998) as Sheherazade
Croupier (1998) as Girl with joint
Monk Dawson (1998) as Mollie
How to Breed Gibbons (1999) as Juliet
Beowulf (1999) as Kyra
Secret Agent Man (2000) as Lacey Sullivan
Party of Five (2000) as Holly Begins
Hollow Man (2000) as Sebastian's Neighbor
Get Carter (2000) as Geraldine
Gideon's Crossing (2000) as Dr. Alejandra 'Ollie' Klein
Ali G Indahouse (2002) as Kate Hedges
Sweet Home Alabama (2002) as Tabatha Wadmore-Smith
Highwaymen (2003) as Molly
The Life of David Gale (2003) as Berlin
Stuck on You (2003) as Bus Stop Bombshell
The Practice (2003) as Tara Wilson
Spartacus (2004) as Varinia
Boston Legal (2004) as Tara Wilson
Nip/Tuck (2005) as Detective Kit McGraw
Skinwalkers (2006) as Rachel Talbot
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Shooter (2007) as Alourdes Galindo
Doomsday (2008) as Eden Sinclair
Underworld: Rise of the Lycans (2009) as Sonja
Stolen (2009) as Barbara
Separation City (2009) as Katrien
Stargate Universe (2010) as Kiva
Re-Uniting the Rubins (2010) as Andie Rubins
The Gates (2010) as Claire Radcliff
Discography
Albums:
Come Alive (1998, produced by Dave Stewart)
Female Icon (1999, produced by Dave Stewart)
Singles:
"Getting Naked" (1997)